Monensin

• CAT Number: M082441
• CAS Number: 17090-79-8
• Molecular Formula: C36H62O11
• Molecular Weight: 670.80
• Purity: ≥95%
• Target: Apoptosis
• Storage: Store at -20°C
• IUPAC Name: (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-[(2R,5S)-5-ethyl-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]oxolan-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-3-methoxy-2-methylpentanoic acid
• InChI: InChI=1S/C36H62O11/c1-10-34(31-20(3)16-26(43-31)28-19(2)15-21(4)36(41,18-37)46-28)12-11-27(44-34)33(8)13-14-35(47-33)17-25(38)22(5)30(45-35)23(6)29(42-9)24(7)32(39)40/h19-31,37-38,41H,10-18H2,1-9H3,(H,39,40)/t19-,20-,21+,22+,23-,24-,25-,26+,27+,28-,29+,30-,31+,33-,34-,35+,36-/m0/s1
• InChIKey: GAOZTHIDHYLHMS-KEOBGNEYSA-N
• SMILES: CC[C@]1(CC[C@@H](O1)[C@@]2(CC[C@@]3(O2)C[C@@H]([C@H]([C@H](O3)[C@@H](C)[C@H]([C@H](C)C(=O)O)OC)C)O)C)[C@H]4[C@H](C[C@@H](O4)[C@@H]5[C@H](C[C@H]([C@@](O5)(CO)O)C)C)C

Monensin（Cat No.:M082441）is a polyether ionophore antibiotic commonly used in veterinary medicine, especially in cattle and poultry, to prevent coccidiosis and promote growth. It works by facilitating the transport of ions across cell membranes, disrupting ion gradients within targeted pathogens like Gram-positive bacteria and protozoa, leading to cell death. Monensin enhances feed efficiency and weight gain by modifying ruminal fermentation, making nutrient absorption more effective. Additionally, it is used in cell biology research to study ion transport mechanisms. Its efficacy and safety in livestock management make it widely utilized in animal agriculture.

Reference

Structure of monensic acid, a new biologically active compound. Agtarap A. et al. J. Am. Chem. Soc. 1967, 89, 5737.Molecular structure of monovalent metal cation complexes of monensin. Pinkerton M. et al. J. Mol. Biol. 1970, 48, 533