Monensin Sodium Salt

• CAT Number: R009571
• CAS Number: 22373-78-0
• Molecular Formula: C36H61O11 • Na
• Molecular Weight: 692.90
• Purity: ≥95%
• Synonyms: 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric Acid Sodium; A 3823A; Coban; Rumensin
• Target: Membrane Transporter/Ion Channel
• Storage: 3 years -20C powder
• IUPAC Name: sodium;(2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-[(2R,5S)-5-ethyl-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]oxolan-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-3-methoxy-2-methylpentanoate
• InChI: InChI=1S/C36H62O11.Na/c1-10-34(31-20(3)16-26(43-31)28-19(2)15-21(4)36(41,18-37)46-28)12-11-27(44-34)33(8)13-14-35(47-33)17-25(38)22(5)30(45-35)23(6)29(42-9)24(7)32(39)40;/h19-31,37-38,41H,10-18H2,1-9H3,(H,39,40);/q;+1/p-1/t19-,20-,21+,22+,23-,24-,25-,26+,27+,28-,29+,30-,31+,33-,34-,35+,36-;/m0./s1
• InChIKey: XOIQMTLWECTKJL-FBZUZRIGSA-M
• SMILES: CC[C@]1(CC[C@@H](O1)[C@@]2(CC[C@@]3(O2)C[C@@H]([C@H]([C@H](O3)[C@@H](C)[C@H]([C@H](C)C(=O)[O-])OC)C)O)C)[C@H]4[C@H](C[C@@H](O4)[C@@H]5[C@H](C[C@H]([C@@](O5)(CO)O)C)C)C.[Na+]

Monensin Sodium Salt（Cat No.:R009571）is an ionophore antibiotic primarily used in veterinary medicine as a feed additive to promote growth and prevent coccidiosis in livestock, especially cattle and poultry. It selectively transports ions across cell membranes, disrupting ion gradients and inhibiting the growth of Gram-positive bacteria and certain protozoa. This action improves feed efficiency and nutrient absorption, leading to enhanced weight gain and productivity in animals. Monensin also plays a role in scientific research, particularly in studying ion transport mechanisms and cellular processes. Its efficacy and cost-effectiveness make it a staple in animal agriculture.

Reference

Butaye, P., Devriese, L. A., & Haesebrouck, F. (2003). Antimicrobial Growth Promoters Used in Animal Feed: Effects of Less Well Known Antibiotics on Gram-Positive Bacteria. Clinical Microbiology Reviews, 16(2), 175–188. http://doi.org/10.1128/CMR.16.2.175-188.2003Łowicki, D., & Huczyński, A. (2013). Structure and Antimicrobial properties of Monensin A and its derivatives: Summary of the achievements. BioMed Research International, 2013, 1–14. doi:10.1155/2013/742149