For research use only. Not for therapeutic Use.
Monoamine oxidase (EC 1.4.3.4) is an enzyme composed of different polypeptides. Monoamine oxidation catalyzes the oxidative deamination of various biological amines in brain and peripheral tissues by producing hydrogen peroxide. Monoamine oxidase plays an important role in maintaining the regulation of synaptic transmission, emotional behavior and other brain functions[1][2].
Monoamine oxidase has some isoenzymes, the most typical of which are monoamine oxidase (MAO) A and MAOB. MAOA is usually inhibited by low concentrations of Clorgyline (HY-14197A) and MAOB is usually inhibited by low concentrations of l-deprenyl[3].
| Catalog Number | I041649 |
| CAS Number | 9001-66-5 |
| Purity | ≥95% |
| Reference | [1]. Shih JC, et al. Monoamine oxidase: from genes to behavior. Annu Rev Neurosci. 1999;22:197-217. [2]. Bortolato M, et al. Monoamine oxidase inactivation: from pathophysiology to therapeutics. Adv Drug Deliv Rev. 2008 Oct-Nov;60(13-14):1527-33. [3]. Youdim MB, et al. The therapeutic potential of monoamine oxidase inhibitors. Nat Rev Neurosci. 2006 Apr;7(4):295-309. |
