For research use only. Not for therapeutic Use.
Monodechlorovancomycin, <sup><span>®</span></sup> is a compound derived from the glycopeptide antibiotic, vancomycin. Monodechlorovancomycin lacks one of two chlorine atoms found in vancomycin but is otherwise identical.</br>Because the molecular structure and spectrum of activity is nearly identical to vancomycin B, the mechanism is presumably the same as vancomycin. Monodechlorovancomycin prevents peptidoglycan synthesis by two separate mechanisms. One mechanism prevents N-acetylmuramic acid (NAM) and N-acetylglucosamine (NAG) from linking together forming the peptidoglycan backbone. The second mechanism prevents crosslinking between amino acid residues in the peptidoglycan chain.
| Catalog Number | R001247 |
| Molecular Formula | C66H76ClN9O24 xHCl (lot specific) |
| Purity | ≥95% |
| Reference | Sun, Li, and Aline C. Lindbeck. /Synthesis, Isolation, and Antibacterial Activities of Monodechlorovancomycins./ The Journal of Antibiotics 57.10 (2004): 691-94. Web. 1 Oct. 2013.</span></p> |
