For research use only. Not for therapeutic Use.
Monodesmethylchlorpheniramine (Cat No.:C000722) is a metabolite of chlorpheniramine, an antihistamine commonly used to alleviate allergy symptoms. It is formed when the body processes chlorpheniramine, resulting in the removal of one methyl group. Monodesmethylchlorpheniramine may still exhibit some antihistaminic activity, though potentially reduced compared to the parent compound. Research could explore its pharmacological effects, interactions with histamine receptors, and contribution to the overall therapeutic profile of chlorpheniramine.
| Catalog Number | C000722 |
| CAS Number | 20619-12-9 |
| Synonyms | γ-(4-Chlorophenyl)-N-methyl-2-pyridinepropanamine; |
| Molecular Formula | C₁₅H₁₇ClN₂ |
| Purity | ≥95% |
| Solubility | Chloroform (Slightly), DMF (Slightly), Methanol (Slightly) |
| Appearance | Colourless to Light Yellow Oil |
| Storage | -20°C, Inert atmosphere |
| IUPAC Name | 3-(4-chlorophenyl)-N-methyl-3-pyridin-2-ylpropan-1-amine |
| InChI | InChI=1S/C15H17ClN2/c1-17-11-9-14(15-4-2-3-10-18-15)12-5-7-13(16)8-6-12/h2-8,10,14,17H,9,11H2,1H3 |
| InChIKey | UICFCNIVUDNZSW-UHFFFAOYSA-N |
| SMILES | CNCCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2 |
| Reference | Roth, F.E., et al.: J. Pharmacol. Exp. Ther., 124, 347 (1958), Smith, R.B., et al.: Toxicol. Appl. Pharmacol., 28, 240 (1974), Eckhart, C.G., et al.: Anal. Profiles Drug Subs., 7, 43 (1978) |
