For research use only. Not for therapeutic Use.
Morantel tartrate（Cat No.:I002895）is a broad-spectrum anthelmintic used primarily in veterinary medicine to treat gastrointestinal nematode infections in livestock. It belongs to the tetrahydropyrimidine class and functions as a cholinergic agonist, causing spastic paralysis in susceptible parasites, leading to their expulsion from the host. The tartrate salt form enhances its solubility and bioavailability, ensuring effective delivery. Morantel tartrate is well-tolerated and exhibits minimal systemic absorption, making it a safe option for regular deworming programs. Its efficacy and safety profile make it a trusted choice in parasite control for livestock management.
| Catalog Number | I002895 |
| CAS Number | 26155-31-7 |
| Synonyms | CP 12009-18;Pyrimidine;UK 2964-18 |
| Molecular Formula | C12H16N2S • C4H6O6 |
| Purity | ≥95% |
| Target | Parasite |
| Solubility | 10 mM in H2O |
| Storage | -20°C |
| IUPAC Name | (2R,3R)-2,3-dihydroxybutanedioic acid;1-methyl-2-[(E)-2-(3-methylthiophen-2-yl)ethenyl]-5,6-dihydro-4H-pyrimidine |
| InChI | InChI=1S/C12H16N2S.C4H6O6/c1-10-6-9-15-11(10)4-5-12-13-7-3-8-14(12)2;5-1(3(7)8)2(6)4(9)10/h4-6,9H,3,7-8H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10)/b5-4+;/t;1-,2-/m.1/s1 |
| InChIKey | GGXQONWGCAQGNA-UUSVNAAPSA-N |
| SMILES | CC1=C(SC=C1)/C=C/C2=NCCCN2C.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O |
| Reference | </br>1:Residue depletion of morantel tartrate in goat tissue and milk. Oriani JA.Vet Hum Toxicol. 1993;35 Suppl 2:62-3. No abstract available. PMID: 8236770 </br>2:Evaluation of the efficacy and safety of morantel tartrate in domestic goats. Reinemeyer CR, Pringle JK.Vet Hum Toxicol. 1993;35 Suppl 2:57-61. No abstract available. PMID: 8236769 </br>3:Morantel tartrate release from a long-acting intraruminal device in cattle: pharmacokinetics and gastrointestinal distribution. Lanusse CE, Gascon LH, Ranjan S, Prichard RK.J Vet Pharmacol Ther. 1992 Jun;15(2):117-23. PMID: 1433473 </br>4:Continued susceptibility of Ostertagia ostertagi infective larvae to morantel tartrate. Tornquist M, Purnell RE, Tolling ST.Vet Rec. 1991 Nov 23;129(21):472. No abstract available. PMID: 1763471 </br>5:Further studies with a strain of Ostertagia ostertagi resistant to morantel tartrate. Borgsteede FH.Int J Parasitol. 1991 Nov;21(7):867-70. PMID: 1774123 </br>6:Reliability and reproducibility of the larval paralysis test as an in vitro method for the detection of anthelmintic resistance of nematodes against levamisole and morantel tartrate. Geerts S, Brandt J, Borgsteede FH, Van Loon H.Vet Parasitol. 1989 Jan;30(3):223-32. PMID: 2705288 </br>7:The difference between two strains of Ostertagia ostertagi in resistance to morantel tartrate. Borgsteede FH.Int J Parasitol. 1988 Jun;18(4):499-502. No abstract available. PMID: 3417377 </br>8:Larvicidal properties against Ostertagia ostertagi of the faeces of calves treated with a sustained release formulation of morantel tartrate. Rossiter LM, Purnell RE, Seymour DJ.Vet Rec. 1988 Jan 23;122(4):81-4. PMID: 3354163 </br>9:Economic value of vitamin A and Exhelm (morantel tartrate) in sheep in Niger. Metzel JC, Lindenmayer JM.Acta Vet Scand Suppl. 1988;84:402-4. No abstract available. PMID: 3232646 </br>10:Field trials with Exhelm (morantel tartrate) and vitamin A in sheep in Niger. Lindenmayer J, Stem E, Marshall D, Sama S.Acta Vet Scand Suppl. 1988;84:151-4. No abstract available. PMID: 3232600 |
