For research use only. Not for therapeutic Use.
Moricizine (morpholine-d8) (Cat No.:R036005)is a deuterated version of Moricizine, where eight hydrogen atoms in the morpholine ring are replaced with deuterium. This isotopic labeling significantly enhances the stability and reduces the metabolic degradation of the molecule, making it highly valuable for pharmacokinetic and metabolic studies of Moricizine. As an antiarrhythmic drug, Moricizine is used to correct abnormal heart rhythms. The deuterated variant, morpholine-d8, allows for precise and detailed investigation into the drug’s absorption, distribution, metabolism, and excretion, improving understanding of its pharmacological profile and aiding in the optimization of therapeutic strategies.
Catalog Number | R036005 |
CAS Number | NA |
Synonyms | N-[10-[3-(4-morpholinyl)-1-oxopropyl]-10H-phenothiazin-2-yl]Carbamic Acid Ethyl Ester-D8; 10-(3-Morpholinopropionyl)phenothiazine-2-carbamic Acid Ethyl Ester-D8; Ethyl 10-(β-N-Morpholinylpropionyl)phenothiazine-2-carbamate-D8; Ethyl 10-(β-Morpholinop |
Molecular Formula | C₂₂H₁₇D₈N₃O₄S |
Purity | ≥95% |
Storage | -20°C |
IUPAC Name | ethyl N-[10-[3-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)propanoyl]phenothiazin-2-yl]carbamate |
InChI | InChI=1S/C22H25N3O4S/c1-2-29-22(27)23-16-7-8-20-18(15-16)25(17-5-3-4-6-19(17)30-20)21(26)9-10-24-11-13-28-14-12-24/h3-8,15H,2,9-14H2,1H3,(H,23,27)/i11D2,12D2,13D2,14D2 |
InChIKey | FUBVWMNBEHXPSU-FUEQIQQISA-N |
SMILES | CCOC(=O)NC1=CC2=C(C=C1)SC3=CC=CC=C3N2C(=O)CCN4CCOCC4 |