MPO-IN-28

• CAT Number: I019059
• CAS Number: 37836-90-1
• Molecular Formula: C₁₁H₁₃N₅O
• Molecular Weight: 231.25
• Purity: ≥95%
• Target: Metabolic Enzyme/Protease

MPO-IN-28 (CAT: I019059), also known as Compound 28, is a potent inhibitor of myeloperoxidase (MPO), an enzyme involved in the oxidative burst of immune cells. With an inhibitory concentration (IC50) of 44 nM, MPO-IN-28 effectively targets and modulates MPO activity. By interfering with MPO-mediated oxidative processes, this compound holds promise for applications in inflammation-related disorders and oxidative stress conditions.

Reference

[1]. Soubhye J, et al. Discovery of Novel Potent Reversible and Irreversible Myeloperoxidase Inhibitors Using Virtual Screening Procedure. J Med Chem. 2017 Aug 10;60(15):6563-6586.