For research use only. Not for therapeutic Use.
MPO-IN-3 is a potent myeloperoxidase (MPO) inhibitor (WO2013068875A1, example 191). Myeloperoxidase (MPO) is a heme-containing enzyme belonging to the peroxidase superfamily[1].
| Catalog Number | I045160 |
| CAS Number | 1435469-45-6 |
| Synonyms | 1-(4-aminobutyl)-6-(2,4-dimethoxyphenyl)-2-sulfanylidenepyrimidin-4-one;hydrochloride |
| Molecular Formula | C16H22ClN3O3S |
| Purity | ≥95% |
| InChI | InChI=1S/C16H21N3O3S.ClH/c1-21-11-5-6-12(14(9-11)22-2)13-10-15(20)18-16(23)19(13)8-4-3-7-17;/h5-6,9-10H,3-4,7-8,17H2,1-2H3,(H,18,20,23);1H |
| InChIKey | VSIRCLPNEYEPPU-UHFFFAOYSA-N |
| SMILES | COC1=CC(=C(C=C1)C2=CC(=O)NC(=S)N2CCCCN)OC.Cl |
| Reference | [1]. Philip Albert Carpino, et al. 2-thiopyrimidinones. WO2013068875A1. |
