For research use only. Not for therapeutic Use.
Mps-BAY2a（Cat No.:I011243）is a selective small-molecule inhibitor of monopolar spindle 1 (Mps1) kinase, a critical regulator of the spindle assembly checkpoint that ensures accurate chromosome segregation during mitosis. By inhibiting Mps1, Mps-BAY2a disrupts proper mitotic progression, leading to chromosomal instability and apoptosis, particularly in rapidly dividing cancer cells. This makes it a promising candidate for cancer therapy, especially in tumors reliant on an intact mitotic checkpoint. Mps-BAY2a is also a valuable research tool for studying mitotic regulation, chromosome dynamics, and potential therapeutic strategies targeting cell division in oncology.
| CAS Number | 1382477-96-4 |
| Synonyms | N-cyclopropyl-4-[8-(2-methylpropylamino)-6-quinolin-5-ylimidazo[1,2-a]pyrazin-3-yl]benzamide |
| Molecular Formula | C29H28N6O |
| Purity | ≥95% |
| IUPAC Name | N-cyclopropyl-4-[8-(2-methylpropylamino)-6-quinolin-5-ylimidazo[1,2-a]pyrazin-3-yl]benzamide |
| InChI | InChI=1S/C29H28N6O/c1-18(2)15-31-27-28-32-16-26(19-8-10-20(11-9-19)29(36)33-21-12-13-21)35(28)17-25(34-27)23-5-3-7-24-22(23)6-4-14-30-24/h3-11,14,16-18,21H,12-13,15H2,1-2H3,(H,31,34)(H,33,36) |
| InChIKey | MDYKTGNHXNTATG-UHFFFAOYSA-N |
| SMILES | CC(C)CNC1=NC(=CN2C1=NC=C2C3=CC=C(C=C3)C(=O)NC4CC4)C5=C6C=CC=NC6=CC=C5 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
