For research use only. Not for therapeutic Use.
Mps1-IN-7(CAT: I024258) is a potent and selective inhibitor of Monopolar spindle 1 (Mps1/TTK), a dual-specificity protein kinase involved in the spindle assembly checkpoint during mitosis. By targeting Mps1, Mps1-IN-7 disrupts proper chromosome alignment and segregation, making it a valuable compound for cancer research, particularly in studies focused on mitotic regulation and aneuploidy. It exhibits strong activity in cell-based assays and is used to investigate the therapeutic potential of Mps1 inhibition in tumor progression and proliferation. Mps1-IN-7 is ideal for exploring cell cycle dynamics and developing targeted anti-cancer strategies.
| CAS Number | 1578244-34-4 |
| Synonyms | 8-N-[(2S)-3,3-dimethylbutan-2-yl]-2-N-[2-methoxy-4-(1-methylpyrazol-4-yl)phenyl]pyrido[3,4-d]pyrimidine-2,8-diamine |
| Molecular Formula | C24H29N7O |
| Purity | ≥95% |
| IUPAC Name | 8-N-[(2S)-3,3-dimethylbutan-2-yl]-2-N-[2-methoxy-4-(1-methylpyrazol-4-yl)phenyl]pyrido[3,4-d]pyrimidine-2,8-diamine |
| InChI | InChI=1S/C24H29N7O/c1-15(24(2,3)4)28-22-21-17(9-10-25-22)12-26-23(30-21)29-19-8-7-16(11-20(19)32-6)18-13-27-31(5)14-18/h7-15H,1-6H3,(H,25,28)(H,26,29,30)/t15-/m0/s1 |
| InChIKey | XTJZKALDRPVFSN-HNNXBMFYSA-N |
| SMILES | CC(C(C)(C)C)NC1=NC=CC2=CN=C(N=C21)NC3=C(C=C(C=C3)C4=CN(N=C4)C)OC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
