For research use only. Not for therapeutic Use.
MQAE is a fluorescent indicator dye that can be used to measure intracellular and extracellular chloride concentrations (absorption/emission max: 350/460 nm).1 It detects the ion via diffusion-limited collisional quenching.
| Catalog Number | M035347 |
| CAS Number | 162558-52-3 |
| Synonyms | MQAE |
| Molecular Formula | C14H16NO3 • Br |
| Purity | ≥95% |
| Storage | -20°C |
| InChI | InChI=1S/C14H16NO3.BrH/c1-3-18-14(16)10-15-8-4-5-11-9-12(17-2)6-7-13(11)15;/h4-9H,3,10H2,1-2H3;1H/q+1;/p-1 |
| InChIKey | DSLLHVISNOIYHR-UHFFFAOYSA-M |
| SMILES | O=C(OCC)C[N+]1=CC=CC2=CC(OC)=CC=C21.[Br-] |
| Reference | </br>1:Two-photon chloride imaging using MQAE in vitro and in vivo. Kovalchuk Y, Garaschuk O.Cold Spring Harb Protoc. 2012 Jul 1;2012(7):778-85. doi: 10.1101/pdb.prot070037. PMID: 22753606 </br>2:Determination of chloride efflux by X-ray microanalysis versus MQAE-fluorescence. Andersson C, Roomans GM.Microsc Res Tech. 2002 Dec 15;59(6):531-5. PMID: 12467030 </br>3:Use of MQAE for measurement of intracellular [Cl-] in cultured aortic smooth muscle cells. Koncz C, Daugirdas JT.Am J Physiol. 1994 Dec;267(6 Pt 2):H2114-23. PMID: 7810712 |
