For research use only. Not for therapeutic Use.
MRGPRX4 modulator-1 (compound 31-2) is a potent mas-related g-protein receptor X4 (MRGPR X4) modulator, with antagonist activity of IC50 < 100 nM for MRGPR4. MRGPRX4 modulator-1 can be used for researching MRGPR X4 dependent diseases such as itch, pain, and autoimmune disorders[1].
| Catalog Number | I043698 |
| CAS Number | 2492596-61-7 |
| Synonyms | 6-[[2-chloro-4-(trifluoromethyl)phenoxy]methyl]-4-ethylpyridine-2-carboxylic acid |
| Molecular Formula | C16H13ClF3NO3 |
| Purity | ≥95% |
| InChI | InChI=1S/C16H13ClF3NO3/c1-2-9-5-11(21-13(6-9)15(22)23)8-24-14-4-3-10(7-12(14)17)16(18,19)20/h3-7H,2,8H2,1H3,(H,22,23) |
| InChIKey | UNHAKUSQBBXQSU-UHFFFAOYSA-N |
| SMILES | CCC1=CC(=NC(=C1)C(=O)O)COC2=C(C=C(C=C2)C(F)(F)F)Cl |
| Reference | [1]. Adam YEAGER, et al. Modulators of mas-related g-protein receptor x4 and related products and methods. WO2020198537 (compound 31-2). |
