For research use only. Not for therapeutic Use.
MRGPRX4 modulator-2 (compound 1-55) is a potent MRGPR X4 modulator, possessing antagonist activity against MRGPR X4 with an IC50 < 100 nM. MRGPRX4 modulator-2 can be used for researching autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson’s Syndrome, and other chronic itch conditions[1].
| Catalog Number | I043532 |
| CAS Number | 2492595-24-9 |
| Synonyms | 3-[[2-chloro-4-(trifluoromethyl)phenoxy]methyl]-2-fluorobenzoic acid |
| Molecular Formula | C15H9ClF4O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H9ClF4O3/c16-11-6-9(15(18,19)20)4-5-12(11)23-7-8-2-1-3-10(13(8)17)14(21)22/h1-6H,7H2,(H,21,22) |
| InChIKey | TWOXPNAILYKJPT-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C(=C1)C(=O)O)F)COC2=C(C=C(C=C2)C(F)(F)F)Cl |
| Reference | [1]. Adam YEAGER, et al. Modulators of mas-related g-protein receptor x4 and related products and methods. WO2020198537A1 (compound 1-55) |
