MRK-898

For research use only. Not for therapeutic Use.

  • CAT Number: I041085
  • CAS Number: 461450-30-6
  • Molecular Formula: C20H9F5N4
  • Molecular Weight: 400.30
  • Purity: ≥95%
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MRK-898(Cat No.:I041085)is a potent, selective inhibitor of the protein kinase cAMP-dependent protein kinase (PKA), which plays a crucial role in various cellular signaling pathways. By inhibiting PKA activity, MRK-898 can modulate processes such as cell growth, metabolism, and gene expression. Preclinical studies suggest that MRK-898 may have therapeutic potential in treating cancers, including those driven by dysregulated PKA activity. Its ability to specifically target PKA makes it a promising candidate for further research in oncology and other diseases where PKA is implicated in disease progression.


CAS Number 461450-30-6
Synonyms

5-fluoro-2-[2-fluoro-5-[7-(trifluoromethyl)imidazo[1,2-a]pyrimidin-3-yl]phenyl]benzonitrile

Molecular Formula C20H9F5N4
Purity ≥95%
IUPAC Name 5-fluoro-2-[2-fluoro-5-[7-(trifluoromethyl)imidazo[1,2-a]pyrimidin-3-yl]phenyl]benzonitrile
InChI InChI=1S/C20H9F5N4/c21-13-2-3-14(12(7-13)9-26)15-8-11(1-4-16(15)22)17-10-27-19-28-18(20(23,24)25)5-6-29(17)19/h1-8,10H
InChIKey XXRKXVKJMSIZSM-UHFFFAOYSA-N
SMILES C1=CC(=C(C=C1C2=CN=C3N2C=CC(=N3)C(F)(F)F)C4=C(C=C(C=C4)F)C#N)F

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