MRS 1754

• CAT Number: I010624
• CAS Number: 264622-58-4
• Molecular Formula: C26H26N6O4
• Molecular Weight: 486.53
• Purity: ≥95%
• Synonyms: N-(4-Cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide
• Target: Adenosine Receptor
• Solubility: Soluble to 5 mM in DMSO with gentle warming and to 10 mM in DMSO with sonication
• Storage: Desiccate at RT
• IUPAC Name: N-(4-cyanophenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide
• InChI: InChI=1S/C26H26N6O4/c1-3-13-31-24-22(25(34)32(14-4-2)26(31)35)29-23(30-24)18-7-11-20(12-8-18)36-16-21(33)28-19-9-5-17(15-27)6-10-19/h5-12H,3-4,13-14,16H2,1-2H3,(H,28,33)(H,29,30)
• InChIKey: AJBBEYXFRYFVNM-UHFFFAOYSA-N
• SMILES: CCCN1C2=C(C(=O)N(C1=O)CCC)NC(=N2)C3=CC=C(C=C3)OCC(=O)NC4=CC=C(C=C4)C#N

MRS 1754 (Cat No.:I010624) is a potent and selective antagonist of the adenosine A2B receptor. It is a small molecule compound that specifically inhibits the activity of the A2B receptor, which plays a role in various physiological processes. By blocking this receptor, MRS 1754 modulates adenosine signaling and interferes with downstream cellular responses. This compound has been widely used in research to study adenosine receptors and their implications in conditions such as inflammation, cardiovascular diseases, and cancer. MRS 1754’s selectivity and potency make it a valuable tool for understanding adenosine receptor function and potential therapeutic applications.