For research use only. Not for therapeutic Use.
MRT68921 is a bioactive chemical.
| Catalog Number | I008198 |
| CAS Number | 1190379-70-4 |
| Synonyms | MRT68921;Cyclobutanecarboxylic acid {3-[2-cyclopropyl-5-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-6-ylamino)-phenylamino]-propyl}-amide |
| Molecular Formula | C25H34N6O |
| Purity | ≥95% |
| Target | ULK |
| Solubility | Soluble in DMSO |
| Storage | Store at -20°C |
| InChIKey | KKISLZKMBSCLSS-UHFFFAOYSA-N |
| SMILES | CN(C1)CCC2=C1C=CC(NC3=NC=C(C4CC4)C(NCCCNC(C5CCC5)=O)=N3)=C2 |
| Reference | </br>1:Petherick KJ, Conway OJ, Mpamhanga C, Osborne SA, Kamal A, Saxty B, Ganley IG. Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy. J Biol Chem. 2015 May 1;290(18):11376-83. doi: 10.1074/jbc.C114.627778. Erratum in: J Biol Chem. 2015 Nov 27;290(48):28726. PubMed PMID: 25833948; PubMed Central PMCID: PMC4416842. |
