For research use only. Not for therapeutic Use.
MS117(CAT: I032801) is a selective BET (bromodomain and extra-terminal domain) inhibitor utilized in epigenetics and cancer research. By targeting BET proteins such as BRD2, BRD3, and BRD4, MS117 disrupts protein-protein interactions critical for transcriptional regulation. This compound plays a significant role in studying gene expression, chromatin remodeling, and the development of targeted therapies for cancers driven by BET protein activity. With its high potency and specificity, MS117 serves as a powerful tool for researchers exploring the therapeutic potential of epigenetic modulation in oncology and related fields.
| Catalog Number | I032801 |
| Synonyms | MS117; MS 117; MS-117; |
| Molecular Formula | C17H22N4O |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | N-(3-(4-(((2-aminoethyl)(methyl)amino)methyl)-1H-pyrrol-3-yl)phenyl)acrylamide |
| InChI | InChI=1S/C17H22N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h3-6,9-11,19H,1,7-8,12,18H2,2H3,(H,20,22) |
| InChIKey | HVDMIAFOVVMNJF-UHFFFAOYSA-N |
| SMILES | O=C(C=C)NC1=CC(C2=CNC=C2CN(C)CCN)=CC=C1 |
