For research use only. Not for therapeutic Use.
MS4078(CAT: I019478) emerges as a promising player in the field of targeted protein degradation, particularly in the context of anaplastic lymphoma kinase (ALK) inhibition. This compound operates as an ALK PROTAC (degrader), showcasing a robust binding affinity to ALK with a Kd of 19 nM. Through its unique mechanism of action, MS4078 has the potential to induce the degradation of ALK proteins, contributing to the modulation of aberrant cellular processes and associated diseases.
| Catalog Number | I019478 |
| CAS Number | 2229036-62-6 |
| Molecular Formula | C₄₅H₅₂ClN₉O₈S |
| Purity | ≥95% |
| Reference | [1]. Zhang C, et al. Proteolysis Targeting Chimeras (PROTACs) of Anaplastic Lymphoma Kinase (ALK). Eur J Med Chem. 2018 May 10;151:304-314. |
