For research use only. Not for therapeutic Use.
MT-DADMe-ImmA (Cat.No:I013706) is a synthetic compound that belongs to the class of nucleoside analogs. It is an inhibitor of the enzyme adenosine kinase and is being studied for its potential therapeutic applications in various diseases, including cancer. MT-DADMe-ImmA shows promise as an anticancer agent by disrupting adenosine metabolism and inhibiting tumor growth. Further research is ongoing to explore its efficacy and safety profile.
| Catalog Number | I013706 |
| CAS Number | 653592-04-2 |
| Molecular Formula | C₁₃H₁₉N₅OS |
| Purity | ≥95% |
| Target | Others |
| Solubility | DMSO |
| IUPAC Name | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-(methylsulfanylmethyl)pyrrolidin-3-ol |
| InChI | InChI=1S/C13H19N5OS/c1-20-6-9-4-18(5-10(9)19)3-8-2-15-12-11(8)16-7-17-13(12)14/h2,7,9-10,15,19H,3-6H2,1H3,(H2,14,16,17)/t9-,10+/m1/s1 |
| InChIKey | NTHMDFGHOCNNOE-ZJUUUORDSA-N |
| SMILES | CSCC1CN(CC1O)CC2=CNC3=C2N=CN=C3N |
| Reference | [1]. Evans GB, et al. Second generation transition state analogue inhibitors of human 5//’-methylthioadenosine phosphorylase. J Med Chem. 2005 Jul 14;48(14):4679-89.<br>[2]. Basu I, et al. A transition state analogue of 5//’-methylthioadenosine phosphorylase induces apoptosis in head and neck cancers. J Biol Chem. 2007 Jul 20;282(29):21477-86. |
