For research use only. Not for therapeutic Use.
MTX-211 is a dual inhibitor of EGFR and PI3K. Potentially useful for treatment of KRAS mutant colorectal cancer.
| Catalog Number | I005983 |
| CAS Number | 1952236-05-3 |
| Synonyms | N-[2-chloro-5-[4-(3-chloro-4-fluoroanilino)quinazolin-6-yl]pyridin-3-yl]methanesulfonamide |
| Molecular Formula | C₂₀H₁₄Cl₂FN₅O₂S |
| Purity | ≥95% |
| Target | Protein Tyrosine Kinase/RTK |
| Solubility | DMSO |
| Storage | -20°C |
| InChI | InChI=1S/C20H14Cl2FN5O2S/c1-31(29,30)28-18-7-12(9-24-19(18)22)11-2-5-17-14(6-11)20(26-10-25-17)27-13-3-4-16(23)15(21)8-13/h2-10,28H,1H3,(H,25,26,27) |
| InChIKey | GUYKCXXNIKKSBC-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)NC1=C(N=CC(=C1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)F)Cl)Cl |
