Mupirocin

• CAT Number: A000125
• CAS Number: 12650-69-0
• Molecular Formula: C26H44O9
• Molecular Weight: 500.63
• Purity: ≥95%
• Synonyms: Pseudomonic acid; 12650-69-0; Bactroban; Mupirocine; Mupirocinum
• Target: Bacterial
• Solubility: >22.8mg/mL in DMSO
• Storage: Store at -20°C
• IUPAC Name: 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl]oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid
• InChI: InChI=1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1
• InChIKey: MINDHVHHQZYEEK-HBBNESRFSA-N
• SMILES: CC(C1C(O1)CC2COC(C(C2O)O)CC(=CC(=O)OCCCCCCCCC(=O)O)C)C(C)O

Mupirocin（Cat No.:A000125）is a topical antibiotic derived from the bacterium Pseudomonas fluorescens. It is widely used to treat skin infections, such as impetigo and secondary infections of traumatic skin lesions. Mupirocin works by inhibiting bacterial protein synthesis through binding to isoleucyl-tRNA synthetase, leading to the suppression of bacterial growth. Its broad-spectrum activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), makes it an essential tool in managing resistant infections. Mupirocin’s efficacy and safety profile ensure its prominence in dermatological and wound care treatments.

Overview of Clinical Research

Mupirocin is a protein synthesis inhibitor used to treat skin and soft tissue infections.