MuRF1-IN-2

• CAT Number: I040647
• CAS Number: 937891-74-2
• Molecular Formula: C23H22N2O7
• Molecular Weight: 438.43
• Purity: ≥95%
• Synonyms: [1-(methylcarbamoylamino)-1-oxopropan-2-yl] 4-[(4-methyl-2-oxochromen-7-yl)oxymethyl]benzoate
• InChI: InChI=1S/C23H22N2O7/c1-13-10-20(26)32-19-11-17(8-9-18(13)19)30-12-15-4-6-16(7-5-15)22(28)31-14(2)21(27)25-23(29)24-3/h4-11,14H,12H2,1-3H3,(H2,24,25,27,29)
• InChIKey: QPLWJVFJFYAMHG-UHFFFAOYSA-N
• SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)OCC3=CC=C(C=C3)C(=O)OC(C)C(=O)NC(=O)NC

MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor. MuRF1-IN-2 can be used for research of muscle wasting conditions, of skeletal or cardial muscle atrophy[1].

Reference

[1]. Adams, Volker, et al. Preparation of chromen-2-one compounds suitable for the treatment and prophylaxis of muscle wasting and other conditions. Patent. WO2021032643.