For research use only. Not for therapeutic Use.
Muscarine chloride (Cat.No:I014488) is a toxic alkaloid found in Amanita muscaria (fly fungus) and other fungi of the Inocybe species. It is the first parasympathomimetic substance ever studied and causes profound parasympathetic activation that may end in convulsions and death. The specific antidote is atropine.
| Catalog Number | I014488 |
| CAS Number | 2303-35-7 |
| Synonyms | Muscarine chloride; L-(+)-Muscarine chloride; (+)-Muscarine chloride; EINECS 218-963-2; HSDB 3515; HSDB-3515; HSDB3515;;1-((2S,4R,5S)-4-hydroxy-5-methyltetrahydrofuran-2-yl)-N,N,N-trimethylmethanaminium chloride |
| Molecular Formula | C9H20ClNO2 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Soluble in DMSO |
| InChI | InChI=1S/C9H20NO2.ClH/c1-7-9(11)5-8(12-7)6-10(2,3)4;/h7-9,11H,5-6H2,1-4H3;1H/q+1;/p-1/t7-,8-,9+;/m0./s1 |
| InChIKey | WUFRNEJYZWHXLC-CTERPIQNSA-M |
| SMILES | C[C@H]1[C@H](O)C[C@@H](C[N+](C)(C)C)O1.[Cl-] |
| Reference | </br>1: Eyer P. The role of oximes in the management of organophosphorus pesticide poisoning. Toxicol Rev. 2003;22(3):165-90. Review. PubMed PMID: 15181665.</br>2: Cinca J, Rodríguez-Sinovas A. Cardiovascular reflex responses induced by epicardial chemoreceptor stimulation. Cardiovasc Res. 2000 Jan 1;45(1):163-71. Review. PubMed PMID: 10728330.</br>3: Schwantes U, Topfmeier P. Importance of pharmacological and physicochemical properties for tolerance of antimuscarinic drugs in the treatment of detrusor instability and detrusor hyperreflexia–chances for improvement of therapy. Int J Clin Pharmacol Ther. 1999 May;37(5):209-18. Review. PubMed PMID: 10363619.</br>4: Finkbeiner AE, Bissada NK, Welch LT. Uropharmacology: v. choline esters and other parasympathomimetic drugs. Urology. 1977 Jul;10(1):83-9. Review. PubMed PMID: 17940. </br> </br> |
