For research use only. Not for therapeutic Use.
Mutant p53 modulator-1 is a mutant p53 modulator. Mutant p53 modulator-1 reduces the progression of cancers that contain a p53 mutation (extracted from patent WO2021231474A1, compound 231B)[1].
| Catalog Number | I043856 |
| CAS Number | 2746371-35-5 |
| Synonyms | 1-tert-butyl-N-[[3-[4-[[(3S,4R)-3-fluoro-1-methylpiperidin-4-yl]amino]-1-(2,2,2-trifluoroethyl)indol-2-yl]-1,2,4-oxadiazol-5-yl]methyl]pyrazole-4-carboxamide |
| Molecular Formula | C27H32F4N8O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C27H32F4N8O2/c1-26(2,3)39-13-16(11-33-39)25(40)32-12-23-35-24(36-41-23)22-10-17-19(34-20-8-9-37(4)14-18(20)28)6-5-7-21(17)38(22)15-27(29,30)31/h5-7,10-11,13,18,20,34H,8-9,12,14-15H2,1-4H3,(H,32,40)/t18-,20+/m0/s1 |
| InChIKey | APGSTYOSWBCZAT-AZUAARDMSA-N |
| SMILES | CC(C)(C)N1C=C(C=N1)C(=O)NCC2=NC(=NO2)C3=CC4=C(C=CC=C4N3CC(F)(F)F)NC5CCN(CC5F)C |
| Reference | [1]. Binh Vu, et al. METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION. Patent WO2021231474A1. |
