For research use only. Not for therapeutic Use.
MVN38807 (also referred to as Y-1)（Cat No.:I032904）is an advanced neuraminidase inhibitor developed specifically to target the H1N1 influenza virus. With an IC50 value of 0.21 μM, it shows enhanced inhibitory activity compared to traditional antivirals like oseltamivir carboxylate. This potent inhibition of neuraminidase disrupts viral replication, making MVN38807 an ideal candidate for tackling influenza strains, particularly those with resistance to existing treatments. This compound’s development underscores significant progress in antiviral research, offering promising avenues for more effective influenza management strategies.
| Catalog Number | I032904 |
| CAS Number | 2379438-80-7 |
| Synonyms | Y-1; Y1; Y 1; MVN38807; MVN-38807; MVN 38807; |
| Molecular Formula | C14H11N3O6 |
| Purity | 98% |
| Target | Influenza Virus |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 3,5-dihydroxy-N-[(E)-(4-hydroxy-3-nitrophenyl)methylideneamino]benzamide |
| InChI | InChI=1S/C14H11N3O6/c18-10-4-9(5-11(19)6-10)14(21)16-15-7-8-1-2-13(20)12(3-8)17(22)23/h1-7,18-20H,(H,16,21)/b15-7+ |
| InChIKey | MCGROFKAAXXTBN-VIZOYTHASA-N |
| SMILES | C1=CC(=C(C=C1/C=N/NC(=O)C2=CC(=CC(=C2)O)O)[N+](=O)[O-])O |
| Reference | Yu R, Cheng LP, Li M, Pang W. Discovery of Novel Neuraminidase Inhibitors by Structure-Based Virtual Screening, Structural Optimization, and Bioassay. ACS Med Chem Lett. 2019 Nov 25;10(12):1667-1673. doi: 10.1021/acsmedchemlett.9b00447. PMID: 31857844; PMCID: PMC6912870. |
