MYCMI-6

• CAT Number: I015536
• CAS Number: 681282-09-7
• Molecular Formula: C₂₀H₁₉N₇O
• Molecular Weight: 373.41
• Purity: ≥95%
• Target: c-Myc
• IUPAC Name: 3-[(9-amino-7-ethoxyacridin-3-yl)diazenyl]pyridine-2,6-diamine
• InChI: InChI=1S/C20H19N7O/c1-2-28-12-4-6-15-14(10-12)19(22)13-5-3-11(9-17(13)24-15)26-27-16-7-8-18(21)25-20(16)23/h3-10H,2H2,1H3,(H2,22,24)(H4,21,23,25)
• InChIKey: QNWGRUNKGVWOTA-UHFFFAOYSA-N
• SMILES: CCOC1=CC2=C(C3=C(C=C(C=C3)N=NC4=C(N=C(C=C4)N)N)N=C2C=C1)N

MYCMI-6（Cat No.:I015536）is an investigational small molecule compound that functions as an inhibitor of MYC, a transcription factor often dysregulated in various cancers. MYC is involved in regulating cell growth, proliferation, and metabolism, and its overexpression is linked to the development of many malignancies. MYCMI-6 works by specifically targeting and disrupting the MYC protein’s function, potentially suppressing tumor growth and inducing cell death in MYC-driven cancers. Preclinical studies have shown promising results in inhibiting tumor progression, particularly in hematological and solid cancers. Further clinical trials are needed to evaluate its safety, efficacy, and therapeutic potential.

Reference

[1]. Castell A, et al. A selective high affinity MYC-binding compound inhibits MYC:MAX interaction and MYC-dependent tumor cell proliferation. Sci Rep. 2018 Jul 3;8(1):10064.