For research use only. Not for therapeutic Use.
Mycophenolate mofetil(Cat No.:A001148)is an immunosuppressive drug widely used to prevent organ transplant rejection and treat autoimmune diseases. It is a prodrug of mycophenolic acid, which selectively inhibits inosine monophosphate dehydrogenase (IMPDH), a key enzyme in the de novo synthesis of guanine nucleotides. By blocking this pathway, mycophenolate mofetil suppresses the proliferation of T and B lymphocytes, reducing immune responses. It is commonly used in combination with other immunosuppressants for transplant patients and is also effective in treating conditions like lupus, rheumatoid arthritis, and certain types of vasculitis.
Catalog Number | A001148 |
CAS Number | 128794-94-5 |
Synonyms | RS61443 |
Molecular Formula | C23H31NO7 |
Purity | ≥95% |
Target | Dehydrogenase |
Solubility | >16.3mg/mL in DMSO |
Storage | 3 years -20C powder |
IUPAC Name | 2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate |
InChI | InChI=1S/C23H31NO7/c1-15(5-7-19(25)30-13-10-24-8-11-29-12-9-24)4-6-17-21(26)20-18(14-31-23(20)27)16(2)22(17)28-3/h4,26H,5-14H2,1-3H3/b15-4+ |
InChIKey | RTGDFNSFWBGLEC-SYZQJQIISA-N |
SMILES | CC1=C2COC(=O)C2=C(C(=C1OC)C/C=C(\C)/CCC(=O)OCCN3CCOCC3)O |