For research use only. Not for therapeutic Use.
MyD88-IN-1（Cat No.:I041091）is a selective small molecule inhibitor targeting MyD88, a key adapter protein involved in activating immune responses through Toll-like receptors (TLRs). By blocking MyD88, MyD88-IN-1 aims to suppress the inflammatory signaling pathways that contribute to various autoimmune diseases and chronic inflammatory conditions. This drug is under investigation for its potential to treat diseases such as rheumatoid arthritis, lupus, and other inflammatory disorders. Preclinical studies suggest that MyD88-IN-1 may offer a targeted approach to modulating the immune system with minimal adverse effects, making it a promising candidate in immunotherapy research.
| CAS Number | 2911609-80-6 |
| Synonyms | N-(6-methoxypyridin-3-yl)-3-nitro-4-[4-[(3-nitrophenyl)methyl]piperazin-1-yl]benzenesulfonamide |
| Molecular Formula | C23H24N6O7S |
| Purity | ≥95% |
| IUPAC Name | N-(6-methoxypyridin-3-yl)-3-nitro-4-[4-[(3-nitrophenyl)methyl]piperazin-1-yl]benzenesulfonamide |
| InChI | InChI=1S/C23H24N6O7S/c1-36-23-8-5-18(15-24-23)25-37(34,35)20-6-7-21(22(14-20)29(32)33)27-11-9-26(10-12-27)16-17-3-2-4-19(13-17)28(30)31/h2-8,13-15,25H,9-12,16H2,1H3 |
| InChIKey | LDKDGYNCHLGOIP-UHFFFAOYSA-N |
| SMILES | COC1=NC=C(C=C1)NS(=O)(=O)C2=CC(=C(C=C2)N3CCN(CC3)CC4=CC(=CC=C4)[N+](=O)[O-])[N+](=O)[O-] |
