For research use only. Not for therapeutic Use.
MYF-03-176 is an orally active and potent anticancer agent. MYF-03-176 shows strong antitumor efficacy in MPM mouse xenograft model via oral administration[1].
| Catalog Number | I043519 |
| CAS Number | 2857937-59-6 |
| Synonyms | 2-fluoro-1-[(3R,4R)-3-(pyrimidin-2-ylamino)-4-[[4-(trifluoromethyl)phenyl]methoxy]pyrrolidin-1-yl]prop-2-en-1-one |
| Molecular Formula | C19H18F4N4O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C19H18F4N4O2/c1-12(20)17(28)27-9-15(26-18-24-7-2-8-25-18)16(10-27)29-11-13-3-5-14(6-4-13)19(21,22)23/h2-8,15-16H,1,9-11H2,(H,24,25,26)/t15-,16-/m1/s1 |
| InChIKey | KVAWNRUJSYWYJX-HZPDHXFCSA-N |
| SMILES | C=C(C(=O)N1CC(C(C1)OCC2=CC=C(C=C2)C(F)(F)F)NC3=NC=CC=N3)F |
| Reference | [1]. Mengyang Fan, et al. Covalent Disruptor of YAP-TEAD Association Suppresses Defective Hippo Signaling. BioRxiv. |
