MYF-03-69

• CAT Number: I043520
• CAS Number: 2416418-11-4
• Molecular Formula: C22H20F3N5O2
• Molecular Weight: 443.42
• Purity: ≥95%
• Synonyms: 1-[(3R,4R)-3-(4-pyridin-3-yltriazol-1-yl)-4-[[4-(trifluoromethyl)phenyl]methoxy]pyrrolidin-1-yl]prop-2-en-1-one
• InChI: InChI=1S/C22H20F3N5O2/c1-2-21(31)29-12-19(30-11-18(27-28-30)16-4-3-9-26-10-16)20(13-29)32-14-15-5-7-17(8-6-15)22(23,24)25/h2-11,19-20H,1,12-14H2/t19-,20-/m1/s1
• InChIKey: AZGCPBIUNCLWPF-WOJBJXKFSA-N
• SMILES: C=CC(=O)N1C[C@H]([C@@H](C1)OCC2=CC=C(C=C2)C(F)(F)F)N3C=C(N=N3)C4=CN=CC=C4

MYF-03-69（Cat No.:I043520）is a selective, non-steroidal mineralocorticoid receptor (MR) antagonist developed for the treatment of cardiovascular and renal disorders. By inhibiting the binding of aldosterone to the MR, MYF-03-69 helps regulate sodium retention, blood pressure, and inflammation—key factors in conditions like hypertension, heart failure, and chronic kidney disease. Unlike traditional steroidal MR antagonists, MYF-03-69 offers improved selectivity and a potentially better safety profile with reduced risk of hormonal side effects. It is also a valuable research tool for studying MR signaling pathways and for developing next-generation therapies targeting aldosterone-related pathologies.