myo-Inositol Trispyrophosphate Hexasodium Salt

• CAT Number: R052769
• CAS Number: 23103-35-7
• Molecular Formula: C₆H₆Na₆O₂₁P₆
• Molecular Weight: 737.88
• Purity: ≥95%
• Synonyms: ITTP Hexasodium Salt; myo-Inositol Cyclic 1,2:3,4:5,6-Tris(dihydrogen pyrophosphate)) Hexasodium Salt; myo-Inositol Cyclic 1,2:3,4:5,6-Tris(P,P’-dihydrogen diphosphate) Hexasodium Salt
• Storage: -20°C
• InChI: InChI=1S/C6H12O21P6.6Na/c7-28(8)19-1-2(20-29(9,10)25-28)4-6(24-33(17,18)27-32(15,16)23-4)5-3(1)21-30(11,12)26-31(13,14)22-5;;;;;;/h1-6H,(H,7,8)(H,9,10)(H,11,12)(H,13,14)(H,15,16)(H,17,18);;;;;;/q;6*+1/p-6
• InChIKey: DTOYSAZRROROSE-UHFFFAOYSA-H
• SMILES: C12C(C3C(C4C1OP(=O)(OP(=O)(O4)[O-])[O-])OP(=O)(OP(=O)(O3)[O-])[O-])OP(=O)(OP(=O)(O2)[O-])[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

myo-Inositol Trispyrophosphate Hexasodium Salt (ITPP) is a synthetic derivative of myo-inositol that functions as an allosteric effector of hemoglobin. It enhances the release of oxygen from hemoglobin, thereby increasing oxygen delivery to tissues. ITPP has been explored for its potential therapeutic benefits in conditions characterized by hypoxia, such as cancer, cardiovascular diseases, and certain metabolic disorders. By improving oxygenation in tissues, ITPP may reduce tumor growth in cancer or improve outcomes in ischemic conditions. Its role as a modulator of oxygen transport makes it a promising compound in biomedical research, particularly for its potential applications in oxygen deficiency-related diseases.