Myt1-IN-1

• CAT Number: I044142
• CAS Number: 2719749-02-5
• Molecular Formula: C16H15ClN4O2
• Molecular Weight: 330.77
• Purity: ≥95%
• Synonyms: 2-amino-5-chloro-1-(3-hydroxy-2,6-dimethylphenyl)pyrrolo[2,3-b]pyridine-3-carboxamide
• InChI: InChI=1S/C16H15ClN4O2/c1-7-3-4-11(22)8(2)13(7)21-14(18)12(15(19)23)10-5-9(17)6-20-16(10)21/h3-6,22H,18H2,1-2H3,(H2,19,23)
• InChIKey: QDLIHXNMTGWVGE-UHFFFAOYSA-N
• SMILES: CC1=C(C(=C(C=C1)O)C)N2C(=C(C3=C2N=CC(=C3)Cl)C(=O)N)N

Myt1-IN-1 is a potent Myt1 inhibitor with an IC50 of <10 nM. Myt1-IN-1 has anticancer effects (WO2021195782A1; compound 132)[1].

Reference

[1]. Daniel Durocher, et al. Methods of using myt1 inhibitors. WO2021195782A1.