MZ 472

• CAT Number: I032952
• CAS Number: 54978-27-7
• Molecular Formula: C18H25N5O3
• Molecular Weight: 359.43
• Purity: 98%
• Synonyms: MZ 472; MZ-472; MZ472
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 4H-Pyrido(1,2-a)pyrimidin-4-one, 6,7,8,9-tetrahydro-6-methyl-3-(((2-oxo-3-oxazolidinyl)imino)methyl)-2-(1-piperidinyl)-
• InChI: InChI=1S/C18H25N5O3/c1-13-6-5-7-15-20-16(21-8-3-2-4-9-21)14(17(24)23(13)15)12-19-22-10-11-26-18(22)25/h12-13H,2-11H2,1H3/b19-12+
• InChIKey: BEHZJFKCIRHHBO-XDHOZWIPSA-N
• SMILES: O=C1C(/C=N/N2C(OCC2)=O)=C(N3CCCCC3)N=C4N1C(C)CCC4

MZ 472 (Cat No.: I032952) is a potent, selective dual inhibitor of VEGFR-2 and c-Src tyrosine kinases, showing strong anti-angiogenic and antitumor activity. It disrupts tumor growth by blocking angiogenesis and inhibiting key signaling pathways involved in cancer progression. MZ 472 demonstrates significant efficacy in preclinical cancer models, making it a promising candidate for targeted cancer therapy. Its dual-target mechanism provides enhanced therapeutic potential compared to single-target inhibitors, highlighting its value in oncological research and drug development focused on tumor vascularization and metastasis.

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