For research use only. Not for therapeutic Use.
Potent monoamine oxidase (MAO) inhibitor; (-)-N 0425 is equipotent for MAO-A and MAO-B in vitro. The racemate N 0425 (Axon 1022) and the other enantiomer (+)-N 0425 (Axon 1062) are available as well.
| Catalog Number | I047475 |
| CAS Number | 98640-73-4 |
| Molecular Formula | C14H17N.HCl |
| Purity | ≥95% |
| IUPAC Name | N-methyl-N-prop-2-ynyl-1,2,3,4-tetrahydronaphthalen-2-amine;hydrochloride |
| InChI | InChI=1S/C14H17N.ClH/c1-3-10-15(2)14-9-8-12-6-4-5-7-13(12)11-14;/h1,4-7,14H,8-11H2,2H3;1H |
| SMILES | CN(CC#C)C1CCC2=CC=CC=C2C1.Cl |
| Reference | J. Sterling et al. (R)(+)-N-propargyl-1-aminoindan (rasagiline) and derivatives: highly selective and potent inhibitors of monoamine oxidase B. J. Neural. Transm. Suppl. 1998, 52, 301-305.
B Hazelhoff et al. The neuropharmacological profile of N-methyl-N-propargyl-2-aminotetralin: a potent monoamine oxidase inhibitor. Naunyn-Schmiedeberg’s Arch. Pharmacol. 1985, 330, 50-58.
B. Hazelhoff et al. N-methyl,N-propargyl-2-aminotetralins:novel dopamine agonists with monoamine oxidase inhibiting properties. Eur. J. Pharmacol. 1985, 109, 229-240. |
