N-[2-(4-Hydroxyphenyl)ethyl]acetamide

• CAT Number: R015804
• CAS Number: 1202-66-0
• Molecular Formula: C10H13NO2
• Molecular Weight: 179.22
• Purity: 95%
• Synonyms: N-(p-Hydroxyphenethyl)acetamide; N-(4-Hydroxyphenethyl)acetamide; N-Acetyltyramine; N-[2-(4-Hydroxyphenyl)ethyl]acetamide; N-acetyltyramine
• Target: Bacterial
• Appearance: white solid
• Storage: -20°C
• Analysis method: HPLC
• IUPAC Name: N-[2-(4-hydroxyphenyl)ethyl]acetamide
• InChI: InChI=1S/C10H13NO2/c1-8(12)11-7-6-9-2-4-10(13)5-3-9/h2-5,13H,6-7H2,1H3,(H,11,12)
• InChIKey: ATDWJOOPFDQZNK-UHFFFAOYSA-N
• SMILES: CC(=O)NCCC1=CC=C(C=C1)O

N-Acetyltyramine（Cat No.:R015804）is a quorum sensing inhibitor (QSI) compound naturally produced by Vibrio alginolyticus M3-10. It effectively inhibits the quorum sensing (QS) system of C. violaceum ATCC12472, a bacterium known for its QS-dependent violet pigmentation. N-Acetyltyramine also exhibits the ability to reverse drug resistance in doxorubicin-resistant leukemia P388 cells, indicating its potential as a chemosensitizer in cancer treatment. Its dual activities as a QSI and chemosensitizer make N-Acetyltyramine a promising compound for further research in the fields of antimicrobial agents and cancer therapeutics.