N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly

• CAT Number: I027275
• CAS Number: 64967-39-1
• Molecular Formula: C20H21N3O6
• Molecular Weight: 399.40
• Purity: ≥95%
• Synonyms: 2-[[2-[[(2S)-2-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]acetic acid
• InChI: InChI=1S/C20H21N3O6/c24-17(9-8-15-7-4-10-29-15)23-16(11-14-5-2-1-3-6-14)20(28)22-12-18(25)21-13-19(26)27/h1-10,16H,11-13H2,(H,21,25)(H,22,28)(H,23,24)(H,26,27)/b9-8+/t16-/m0/s1
• InChIKey: ZDLZKMDMBBMJLI-FDMDGMSGSA-N
• SMILES: C1=CC=C(C=C1)CC(C(=O)NCC(=O)NCC(=O)O)NC(=O)C=CC2=CC=CO2

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly (FAPGG) is a synthetic cromogenic substrate for angiotensin converting enzyme (ACE) determination[1].

Reference

[1]. Hsu FL, et al. Both dioscorin, the tuber storage protein of yam (Dioscorea alata cv. Tainong No. 1), and its peptic hydrolysates exhibited angiotensin converting enzyme inhibitory activities. J Agric Food Chem. 2002 Oct 9;50(21):6109-13.
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