N-(3-Desethynylphenyl)-N-(3-bromophenyl) Erlotinib Hydrochloride

• CAT Number: C000132
• CAS Number: 2055840-41-8
• Molecular Formula: C₂₀H₂₂BrN₃O₄ .HCl
• Purity: ≥95%
• Synonyms: N-(3-bromophenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Hydrochloride
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Appearance: White to Pale Yellow Solid
• Storage: 4°C

N-(3-Desethynylphenyl)-N-(3-bromophenyl) Erlotinib Hydrochloride(CAT: C000132) is a chemical compound known for its unique mode of action as an allosteric inhibitor of the enzyme fructose 1,6-bisphosphatase (FBPase). While not a standard pharmaceutical agent, its pharmacologic action involves binding to FBPase at an allosteric site, thereby modulating the enzyme’s activity. This inhibition is of interest in metabolic research and potentially for the development of therapeutic agents targeting conditions related to disrupted glucose metabolism.

Reference

Wright, S.W., et. al.: Bioorg. Med. Chem. Lett., 11, 17 (2000)