N-[4-[2-(2,4-dimethylphenoxy)phenyl]-1,3-thiazol-2-yl]-1,4,5,6-tetrahydropyrimidin-2-amine

For research use only. Not for therapeutic Use.

  • CAT Number: M112182
  • CAS Number: 129639-79-8
  • Molecular Formula: C21H22N4OS
  • Molecular Weight: 378.49
  • Purity: ≥95%
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N-[4-[2-(2,4-dimethylphenoxy)phenyl]-1,3-thiazol-2-yl]-1,4,5,6-tetrahydropyrimidin-2-amine(Cat No.:M112182)is a complex organic compound featuring a thiazole ring, a tetrahydropyrimidine structure, and a 2,4-dimethylphenoxyphenyl group. This molecule consists of multiple heterocyclic components, with the thiazole ring containing sulfur and nitrogen, and the tetrahydropyrimidine serving as a nitrogen-rich bicyclic structure. The compound is likely studied for its potential biological or pharmacological activities, such as enzyme inhibition or receptor interaction, due to the presence of various functional groups and heteroatoms that influence its reactivity and binding properties.


Catalog Number M112182
CAS Number 129639-79-8
Molecular Formula C21H22N4OS
Purity ≥95%
Target Fungal
Storage -20°C
IUPAC Name 4-[2-(2,4-dimethylphenoxy)phenyl]-N-(1,4,5,6-tetrahydropyrimidin-2-yl)-1,3-thiazol-2-amine
InChI InChI=1S/C21H22N4OS/c1-14-8-9-18(15(2)12-14)26-19-7-4-3-6-16(19)17-13-27-21(24-17)25-20-22-10-5-11-23-20/h3-4,6-9,12-13H,5,10-11H2,1-2H3,(H2,22,23,24,25)
InChIKey TYBHXIFFPVFXQW-UHFFFAOYSA-N
SMILES CC1=CC(=C(C=C1)OC2=CC=CC=C2C3=CSC(=N3)NC4=NCCCN4)C
Reference

</br>1: Rouf A, Tanyeli C. Bioactive thiazole and benzothiazole derivatives. Eur J Med Chem. 2015 Jun 5;97:911-27. doi: 10.1016/j.ejmech.2014.10.058. Epub 2014 Oct 22. Review. PubMed PMID: 25455640.</br>2: Tomillero A, Moral MA. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2010 Jan-Feb;32(1):47-86. PubMed PMID: 20383346.</br>3: Borelli C, Schaller M, Niewerth M, Nocker K, Baasner B, Berg D, Tiemann R, Tietjen K, Fugmann B, Lang-Fugmann S, Korting HC. Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungi. Chemotherapy. 2008;54(4):245-59. doi: 10.1159/000142334. Epub 2008 Jun 30. PubMed PMID: 18587237; PubMed Central PMCID: PMC2818358.</br> </br>

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