N-(4-Aminobenzoyl)-L-glutamic acid-d4

• CAT Number: R013174
• CAS Number: 461426-34-6
• Molecular Formula: C12H10D4N2O5
• Molecular Weight: 270.27
• Purity: ≥95%
• Synonyms: (2S)-2-[(4-amino-2,3,5,6-tetradeuteriobenzoyl)amino]pentanedioic acid
• InChI: InChI=1S/C12H14N2O5/c13-8-3-1-7(2-4-8)11(17)14-9(12(18)19)5-6-10(15)16/h1-4,9H,5-6,13H2,(H,14,17)(H,15,16)(H,18,19)/t9-/m0/s1/i1D,2D,3D,4D
• InChIKey: GADGMZDHLQLZRI-SGWYWVALSA-N
• SMILES: [2H]C1=C(C(=C(C(=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)[2H])[2H])N)[2H]

N-(4-Aminobenzoyl)-L-glutamic acid-d4（Cat No.:R013174）is a deuterium-labeled derivative of a folate pathway intermediate, commonly used as a stable isotope-labeled standard in analytical and biochemical studies. The compound features four deuterium atoms, allowing for precise tracking in mass spectrometry-based assays. It is particularly valuable for studying folate metabolism, antifolate drug mechanisms, and enzymatic activity involving folate-related pathways, such as those targeted in cancer and antimicrobial research. N-(4-Aminobenzoyl)-L-glutamic acid-d4 enhances quantification accuracy in pharmacokinetic and metabolic studies, supporting the development of folate-targeted therapeutics and diagnostic applications.