For research use only. Not for therapeutic Use.
Hydronidone, also known as F-351, are Non-Steroidal Antiinflammatory Drugs (NSAIDs) potentially for the treatment of hepatic fibrosis.
| Catalog Number | R004180 |
| CAS Number | 851518-71-3 |
| Synonyms | 1-(4-Hydroxyphenyl)-5-methyl-2(1H)-pyridinone; F 351;? |
| Molecular Formula | C12H11NO2 |
| Purity | ≥95% |
| Storage | -80°C |
| IUPAC Name | 1-(4-hydroxyphenyl)-5-methylpyridin-2-one |
| InChI | InChI=1S/C12H11NO2/c1-9-2-7-12(15)13(8-9)10-3-5-11(14)6-4-10/h2-8,14H,1H3 |
| InChIKey | NETTXQJYJRFTFS-UHFFFAOYSA-N |
| SMILES | CC1=CN(C(=O)C=C1)C2=CC=C(C=C2)O |
| Reference | </br>1: Liu Y, Wu J, Li Z, Luo Y, Zeng F, Shi S. Tolerability and Pharmacokinetics of </br> Hydronidone, an Antifibrotic Agent for Hepatic Fibrosis, after Single and</br> Multiple Doses in Healthy Subjects: an Open-Label, Randomized, Dose-Escalating,</br> First-in-Human Study. Eur J Drug Metab Pharmacokinet. 2017 Feb;42(1):37-48. doi: </br> 10.1007/s13318-015-0316-z. PubMed PMID: 26797810.</br></br> |
