N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymeth

• CAT Number: R023765
• CAS Number: 159857-80-4
• Molecular Formula: C₂₈H₄₀N₆O₇
• Molecular Weight: 572.65
• Purity: ≥95%
• Synonyms: MC-Val-Cit-PAB-OH
• Target: ADC Linker
• Storage: Store at RT
• InChI: InChI=1S/C28H40N6O7/c1-18(2)25(33-22(36)8-4-3-5-16-34-23(37)13-14-24(34)38)27(40)32-21(7-6-15-30-28(29)41)26(39)31-20-11-9-19(17-35)10-12-20/h9-14,18,21,25,35H,3-8,15-17H2,1-2H3,(H,31,39)(H,32,40)(H,33,36)(H3,29,30,41)/t21-,25-/m0/s1
• InChIKey: AMKBTTRWLGVRER-OFVILXPXSA-N
• SMILES: O=C1C=CC(N1CCCCCC(N[C@@H](C(C)C)C(N[C@H](C(NC(C=C2)=CC=C2CO)=O)CCCNC(N)=O)=O)=O)=O

MC-​Val-​Cit-​PAB, also known as MC-​Val-​Cit-​PAB-OH, is a cathepsin cleavable ADC peptide linker. MC-​Val-​Cit-​PAB is useful for making ADC conjugate (antibody-drug conjugate). FDA approved drugs such as brentuximab vedotin used this linker. * * * * * Please also see similar products: #610235: MC-Val-Cit-PAB (ADC peptide linker) and #610234: MC-Val-Cit-PAB-PNP (ADC peptide linker); #620108 Val-cit-PAB-OH (ADC peptide linker).