For research use only. Not for therapeutic Use.
N-Acetyl-D-glucosamine-13C8,15N is 13C and 15N labeled N-Acetyl-D-glucosamine (HY-A0132). N-Acetyl-D-glucosamine is a monosaccharide derivative of glucose.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
| Catalog Number | I040255 |
| Synonyms | N-[(2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxo(1,2,3,4,5,6-13C6)hexan-2-yl]acetamide |
| Molecular Formula | 13C8H1515NO6 |
| Purity | ≥95% |
| InChI | InChI=1S/C8H15NO6/c1-4(12)9-5(2-10)7(14)8(15)6(13)3-11/h2,5-8,11,13-15H,3H2,1H3,(H,9,12)/t5-,6+,7+,8+/m0/s1/i1+1,2+1,3+1,4+1,5+1,6+1,7+1,8+1,9+1 |
| InChIKey | MBLBDJOUHNCFQT-MCDNSCKWSA-N |
| SMILES | CC(=O)NC(C=O)C(C(C(CO)O)O)O |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Slawson C, et al. O-GlcNAc cycling: how a single sugar post-translational modification is changing the way we think about signaling networks. J Cell Biochem. 2006 Jan 1;97(1):71-83. |
