N-Acetyl Sulfamethoxazole

• CAT Number: R010581
• CAS Number: 21312-10-7
• Molecular Formula: C12H13N3O4S
• Molecular Weight: 295.31
• Purity: ≥95%
• Synonyms: N-[4-[[(5-Methyl-3-isoxazolyl)amino]sulfonyl]phenyl]acetamide; 4’-Acetyl-3-sulfa-5-methylisoxazole; N4-Acetylsulfamethoxazole; N4-Acetylsulfisomezole; STX 606; Sulfisomezole-N4-acetate
• Target: Bacterial
• Storage: -20°C
• IUPAC Name: N-[4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]phenyl]acetamide
• InChI: InChI=1S/C12H13N3O4S/c1-8-7-12(14-19-8)15-20(17,18)11-5-3-10(4-6-11)13-9(2)16/h3-7H,1-2H3,(H,13,16)(H,14,15)
• InChIKey: GXPIUNZCALHVBA-UHFFFAOYSA-N
• SMILES: CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)NC(=O)C

N-Acetyl Sulfamethoxazole（Cat No.:R010581）is a metabolite of the antibiotic sulfamethoxazole, formed in the liver through acetylation. This compound is an inactive form of sulfamethoxazole and is primarily excreted through the kidneys. Although it lacks the antibacterial properties of its parent compound, N-Acetyl Sulfamethoxazole is essential in pharmacokinetic studies to understand drug metabolism, distribution, and excretion. Monitoring this metabolite helps assess renal function and potential drug interactions in patients undergoing treatment with sulfamethoxazole, aiding in the optimization of therapeutic regimens in clinical and research settings.