N-Arachidonoyl-L-Alanine

• CAT Number: R067704
• CAS Number: 401941-73-9
• Molecular Formula: C23H37NO3
• Molecular Weight: 375.6
• Purity: ≥95%
• Synonyms: NALA
• Storage: -20°C
• InChI: InChI=1S/C23H37NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-22(25)24-21(2)23(26)27/h7-8,10-11,13-14,16-17,21H,3-6,9,12,15,18-20H2,1-2H3,(H,24,25)(H,26,27)/b8-7-,11-10-,14-13-,17-16-
• InChIKey: ZECSOKFEQQDUCP-ZKWNWVNESA-N
• SMILES: CCCCC/C=CC/C=CC/C=CC/C=CCCCC(N([C@@H](C)C(O)=O)[H])=O

Several different arachidonoyl amino acids, including N-<wbr></wbr>arachidonoyl-<wbr></wbr>L-<wbr></wbr>alanine (NALA), have been isolated and characterized from bovine brain. The glycine congener (NAGly) was further characterized and found to suppress formalin-<wbr></wbr>induced pain in rats. NALA may have activity at cannabinoid receptor and/or VR1, but has not been fully characterized to date.

Reference

1.Huang, S.M.,Bisogno, T.,Petros, T.J., et al. Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain. The Journal of Biological Chemisty 276(46), 42639-42644 (2001).