N-Boc-N-bis(PEG2-OH)

• CAT Number: I017218
• CAS Number: 275385-03-0
• Molecular Formula: C13H27NO6
• Molecular Weight: 293.36
• Purity: ≥95%
• Synonyms: tert-butyl N,N-bis[2-(2-hydroxyethoxy)ethyl]carbamate
• InChI: InChI=1S/C13H27NO6/c1-13(2,3)20-12(17)14(4-8-18-10-6-15)5-9-19-11-7-16/h15-16H,4-11H2,1-3H3
• InChIKey: QKKAOQUTADWQAZ-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N(CCOCCO)CCOCCO

N-Boc-N-bis(PEG2-OH) is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-N-bis(PEG2-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Reference

[1]. Deqiang A, et al. Process for preparation of tetramaleimide linker and application. WO2019033773A1.