N-Boc-PEG2-bromide

• CAT Number: I016985
• CAS Number: 164332-88-1
• Molecular Formula: C₉H₁₈BrNO₃
• Molecular Weight: 268.15
• Purity: ≥95%
• Target: PROTAC
• Storage: -20°C
• IUPAC Name: tert-butyl N-[2-(2-bromoethoxy)ethyl]carbamate
• InChI: InChI=1S/C9H18BrNO3/c1-9(2,3)14-8(12)11-5-7-13-6-4-10/h4-7H2,1-3H3,(H,11,12)
• InChIKey: DMOPZPBTLCZSGL-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NCCOCCBr

N-Boc-PEG2-bromide (Cat No.:I016985) is a PROTAC linking bridge, which belongs to PEG class and Alkyl/ether class. N-Boc-PEG2-bromide can be used to synthesize a series of PROTAC molecules in Chemicalbook. N-Boc-PEG2-bromide is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).

Reference

[1]. Ruben HERRENDORFF, et al. Carbohydrate ligands that bind to antibodies against glycoepitopes of glycosphingolipids. WO2017046172A1.