N-Boc-PEG6-alcohol

• CAT Number: I016702
• CAS Number: 331242-61-6
• Molecular Formula: C₁₇H₃₅NO₈
• Molecular Weight: 381.46
• Purity: ≥95%
• Target: PROTAC
• IUPAC Name: tert-butyl N-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
• InChI: InChI=1S/C17H35NO8/c1-17(2,3)26-16(20)18-4-6-21-8-10-23-12-14-25-15-13-24-11-9-22-7-5-19/h19H,4-15H2,1-3H3,(H,18,20)
• InChIKey: JJZYGSPDXUBTNO-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCO

N-Boc-PEG6-alcohol (Cat No.:I016702) is a PROTAC linking bridge, which belongs to the PEG class and Alkyl/ether class. N-Boc-PEG6-alcohol can be used to synthesize a series of PROTAC molecules in Chemicalbook. N-Boc-PEG6-alcohol is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).

Reference

[1]. Nello Mainolfi, wt al. Irak degraders and uses thereof. US20190192668A1.