For research use only. Not for therapeutic Use.
N-Boc-PEG8-alcohol (CAT: I016597) is a versatile PEG derivative, serving as a crucial building block in the synthesis of PROTACs. With a well-defined polyethylene glycol (PEG) chain and a protected alcohol functional group, this compound acts as a linker to connect various molecular entities in PROTAC designs. Through its incorporation, N-Boc-PEG8-alcohol facilitates the creation of bifunctional molecules that simultaneously engage a target protein of interest and an E3 ligase, promoting the targeted degradation of specific proteins.
| Catalog Number | I016597 |
| CAS Number | 1345337-22-5 |
| Molecular Formula | C₂₁H₄₃NO₁₀ |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
