N-Butyrylglycine

• CAT Number: R057066
• CAS Number: 20208-73-5
• Molecular Formula: C6H11NO3
• Molecular Weight: 145.16
• Purity: ≥95%
• Synonyms: 2-(butanoylamino)acetic acid
• InChI: InChI=1S/C6H11NO3/c1-2-3-5(8)7-4-6(9)10/h2-4H2,1H3,(H,7,8)(H,9,10)
• InChIKey: WPSSBBPLVMTKRN-UHFFFAOYSA-N
• SMILES: CCCC(=O)NCC(=O)O

N-Butyrylglycine（Cat No.:R057066）is an acyl glycine derivative formed by conjugating butyric acid with glycine. It is a white crystalline solid with a melting point of 66-69 °C and is soluble in water and inorganic acids. This compound serves as a minor metabolite in fatty acid metabolism and is produced via the action of glycine N-acyltransferase. Elevated levels of N-butyrylglycine have been associated with certain metabolic disorders, such as ethylmalonic encephalopathy, indicating its potential as a biomarker for diagnosing mitochondrial fatty acid β-oxidation deficiencies. In biochemical research, N-butyrylglycine is utilized to assess specific metabolic pathways, including pyruvate and isovaleryl-CoA metabolism.